Medical Researches
Moderately Effective
Based on 8 Researches
Inositol boosts growth and healthInositol Inclusion Affects Growth, Body Composition, Antioxidant Performance, and Lipid Metabolism of Largemouth Bass ().
Mixed effects on cholesterol levels
We explored how inositol affects growth performance and cholesterol levels in largemouth bass through a systematic diet study. By preparing six different diets with varying inositol concentrations, we fed the fish for eight weeks and closely monitored their progress. The results showed that our group consuming 250 mg/kg of inositol enjoyed significantly better weight gain, growth rates, and feed efficiency compared to the control group.
Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.
Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.
Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
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We tested the effectiveness of a food supplement combining glucomannan, D-chiro-inositol, blume, and inulin in managing high cholesterol levels among individuals with metabolic syndrome. Fifty-eight participants, each dealing with either type 2 diabetes or impaired glucose tolerance, took this supplement daily for four months alongside their metformin medication.
Over the course of the study, we observed significant improvements in several key health markers. The participants experienced a marked reduction in their body weight and body mass index (BMI). More importantly for those dealing with high cholesterol, the supplement contributed to noteworthy enhancements in their lipid profiles. Levels of total cholesterol reduced significantly, alongside improvements in triglycerides and low-density lipoprotein (LDL).
Our findings suggest that this food supplement may be a beneficial addition to traditional treatments for managing cholesterol levels and other risk factors associated with metabolic syndrome. This study highlights the potential of inositol as part of a multi-ingredient supplement, although the specific effect of inositol alone wasn't isolated.
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D--Inositol reduces cholesterol levelsD--Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition.
Study shows significant lipid impact
We examined how D--Inositol (DCI), a natural compound found in many living organisms, influences high cholesterol and obesity, especially when combined with a high-fat diet. In our study involving mice over a 12-week period, we observed that DCI supplementation led to noticeable reductions in body weight, triglycerides, total cholesterol, insulin, and fasting glucose levels when given at doses of 50 and 100 mg per kg daily.
The findings were encouraging as DCI not only diminished body weight but also helped lower fat accumulation in the liver and fat tissue. Importantly, we noted a significant increase in serum adiponectin levels, a beneficial hormone linked to improved lipid metabolism. This increase was accompanied by enhanced activity of adiponectin receptors in the liver, which play a key role in regulating fat and energy metabolism.
Additionally, DCI was shown to activate a critical pathway involving AMPKα and PPARs, further promoting healthy fat management in the body. These results suggest that DCI could be a valuable ally in addressing cholesterol and obesity issues, potentially through its influence on adiponectin synthesis and its related metabolic pathways.
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We wanted to understand how myo-inositol (MI), a compound found in many foods, influences cholesterol levels and overall metabolic health in db/db mice, a commonly used model for type 2 diabetes. Our findings revealed that providing MI significantly reduced high cholesterol and triglyceride levels in these mice, making a noticeable impact on their lipid profiles.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
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Inositol and cholesterol managementCombined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial.
Moderate relevance for inositol effects
This study aimed to explore how a combination of myo-inositol and d-chiro-inositol, along with α-lactalbumin, Gymnema sylvestre, and zinc, impacts cholesterol levels in patients with type 2 diabetes mellitus (T2DM).
We evaluated 75 participants who were randomly assigned to either the supplement group or a placebo group. While we found no significant improvements in blood glucose levels between the two groups overall, the results for cholesterol were more promising.
After three months of supplementation, those taking the combination of nutrients experienced a noticeable reduction in total cholesterol and LDL (or bad cholesterol) levels. In a subgroup of patients who kept their diabetes medications unchanged, cholesterol improvements continued to show after six months.
Additionally, members of the supplement group also saw better weight management and enhancements in their HDL (good cholesterol) and triglyceride levels after three months. These findings suggest that combining these specific nutrients could be beneficial in managing cholesterol levels for those with T2DM.
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User Reviews
This large package lasts four months for adults, providing good value. The small capsules are easy to swallow, and taken half an hour before breakfast, the theanine works as a relaxant without causing drowsiness, instead boosting energy and mitigating depressive symptoms. The addition of inositol helps reduce high cholesterol and supports heart health.
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This L-Theanine works remarkably well during stressful times. It's a natural alternative to anxiety and depression medications that I've relied on for years. I take it for a few weeks, then stop until I need it again. It’s proven effective and I highly recommend it.
This natural antidepressant effectively eliminates stress and boosts cognitive abilities. It strengthens the immune system and improves mood without sedative effects. Theanine supports mental performance, normalises blood pressure, boosts dopamine levels, and reduces the risk of high cholesterol, diabetes, and promotes relaxation.
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Cognitive function support
This product aids relaxation while keeping me alert and promotes healthy cognitive function. The high-quality ingredients, particularly L-Theanine, help with vascular function and maintain acceptable taste. It doesn’t affect my training or muscles and assists in managing high cholesterol effectively.
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