5/24/2025
Last update
5/24/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
USERS' SCORE
Good
Based on 5 Reviews
8.3
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
L-Theanine
200 mg
*
Inositol
100 mg
*
Top Medical Research Studies
9
IP6 improves cholesterol levels
We examined the effects of inositol hexakisphosphate (IP6) and myo-inositol on high cholesterol in rats. In our study, we found that dietary IP6 effectively reduced increased cholesterol levels caused by a specific chemical exposure, while myo-inositol did not show significant benefits.
Additionally, IP6 also contributed to body weight gain, regardless of other dietary factors. Overall, while both inositol types helped prevent fatty liver, only IP6 demonstrated a clear advantage in managing hypercholesterolemia.
Additionally, IP6 also contributed to body weight gain, regardless of other dietary factors. Overall, while both inositol types helped prevent fatty liver, only IP6 demonstrated a clear advantage in managing hypercholesterolemia.
Read More
9
We explored how inositol affects growth performance and cholesterol levels in largemouth bass through a systematic diet study. By preparing six different diets with varying inositol concentrations, we fed the fish for eight weeks and closely monitored their progress. The results showed that our group consuming 250 mg/kg of inositol enjoyed significantly better weight gain, growth rates, and feed efficiency compared to the control group.
Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.
Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.
Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.
Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.
Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
Read More
9
We examined how D--Inositol (DCI), a natural compound found in many living organisms, influences high cholesterol and obesity, especially when combined with a high-fat diet. In our study involving mice over a 12-week period, we observed that DCI supplementation led to noticeable reductions in body weight, triglycerides, total cholesterol, insulin, and fasting glucose levels when given at doses of 50 and 100 mg per kg daily.
The findings were encouraging as DCI not only diminished body weight but also helped lower fat accumulation in the liver and fat tissue. Importantly, we noted a significant increase in serum adiponectin levels, a beneficial hormone linked to improved lipid metabolism. This increase was accompanied by enhanced activity of adiponectin receptors in the liver, which play a key role in regulating fat and energy metabolism.
Additionally, DCI was shown to activate a critical pathway involving AMPKα and PPARs, further promoting healthy fat management in the body. These results suggest that DCI could be a valuable ally in addressing cholesterol and obesity issues, potentially through its influence on adiponectin synthesis and its related metabolic pathways.
The findings were encouraging as DCI not only diminished body weight but also helped lower fat accumulation in the liver and fat tissue. Importantly, we noted a significant increase in serum adiponectin levels, a beneficial hormone linked to improved lipid metabolism. This increase was accompanied by enhanced activity of adiponectin receptors in the liver, which play a key role in regulating fat and energy metabolism.
Additionally, DCI was shown to activate a critical pathway involving AMPKα and PPARs, further promoting healthy fat management in the body. These results suggest that DCI could be a valuable ally in addressing cholesterol and obesity issues, potentially through its influence on adiponectin synthesis and its related metabolic pathways.
Read More
Most Useful Reviews
9
Effective relaxant
3 people found this helpful
This large package lasts four months for adults, providing good value. The small capsules are easy to swallow, and taken half an hour before breakfast, the theanine works as a relaxant without causing drowsiness, instead boosting energy and mitigating depressive symptoms. The addition of inositol helps reduce high cholesterol and supports heart health.
Read More
7.5
Stress relief benefits
1 people found this helpful
This natural antidepressant effectively eliminates stress and boosts cognitive abilities. It strengthens the immune system and improves mood without sedative effects. Theanine supports mental performance, normalises blood pressure, boosts dopamine levels, and reduces the risk of high cholesterol, diabetes, and promotes relaxation.
Read More
7.5
Calmness achieved
10 people found this helpful
It genuinely works. The quality is excellent, and after 2-3 weeks of use, I felt much calmer. I previously suffered from anxiety and panic attacks, but now, having taken it for three months, I feel significantly more relaxed. The benefits are immense, and I highly recommend it. The packaging is convenient, and the tablet size is easy to manage. I’ve noticed an increase in my overall energy throughout the day, and I'm glad to have it with me.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
- All Researches
9
We explored how inositol affects growth performance and cholesterol levels in largemouth bass through a systematic diet study. By preparing six different diets with varying inositol concentrations, we fed the fish for eight weeks and closely monitored their progress. The results showed that our group consuming 250 mg/kg of inositol enjoyed significantly better weight gain, growth rates, and feed efficiency compared to the control group.
Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.
Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.
Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.
Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.
Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
Read More
9
We tested the effectiveness of a food supplement combining glucomannan, D-chiro-inositol, blume, and inulin in managing high cholesterol levels among individuals with metabolic syndrome. Fifty-eight participants, each dealing with either type 2 diabetes or impaired glucose tolerance, took this supplement daily for four months alongside their metformin medication.
Over the course of the study, we observed significant improvements in several key health markers. The participants experienced a marked reduction in their body weight and body mass index (BMI). More importantly for those dealing with high cholesterol, the supplement contributed to noteworthy enhancements in their lipid profiles. Levels of total cholesterol reduced significantly, alongside improvements in triglycerides and low-density lipoprotein (LDL).
Our findings suggest that this food supplement may be a beneficial addition to traditional treatments for managing cholesterol levels and other risk factors associated with metabolic syndrome. This study highlights the potential of inositol as part of a multi-ingredient supplement, although the specific effect of inositol alone wasn't isolated.
Over the course of the study, we observed significant improvements in several key health markers. The participants experienced a marked reduction in their body weight and body mass index (BMI). More importantly for those dealing with high cholesterol, the supplement contributed to noteworthy enhancements in their lipid profiles. Levels of total cholesterol reduced significantly, alongside improvements in triglycerides and low-density lipoprotein (LDL).
Our findings suggest that this food supplement may be a beneficial addition to traditional treatments for managing cholesterol levels and other risk factors associated with metabolic syndrome. This study highlights the potential of inositol as part of a multi-ingredient supplement, although the specific effect of inositol alone wasn't isolated.
Read More
9
We examined how D--Inositol (DCI), a natural compound found in many living organisms, influences high cholesterol and obesity, especially when combined with a high-fat diet. In our study involving mice over a 12-week period, we observed that DCI supplementation led to noticeable reductions in body weight, triglycerides, total cholesterol, insulin, and fasting glucose levels when given at doses of 50 and 100 mg per kg daily.
The findings were encouraging as DCI not only diminished body weight but also helped lower fat accumulation in the liver and fat tissue. Importantly, we noted a significant increase in serum adiponectin levels, a beneficial hormone linked to improved lipid metabolism. This increase was accompanied by enhanced activity of adiponectin receptors in the liver, which play a key role in regulating fat and energy metabolism.
Additionally, DCI was shown to activate a critical pathway involving AMPKα and PPARs, further promoting healthy fat management in the body. These results suggest that DCI could be a valuable ally in addressing cholesterol and obesity issues, potentially through its influence on adiponectin synthesis and its related metabolic pathways.
The findings were encouraging as DCI not only diminished body weight but also helped lower fat accumulation in the liver and fat tissue. Importantly, we noted a significant increase in serum adiponectin levels, a beneficial hormone linked to improved lipid metabolism. This increase was accompanied by enhanced activity of adiponectin receptors in the liver, which play a key role in regulating fat and energy metabolism.
Additionally, DCI was shown to activate a critical pathway involving AMPKα and PPARs, further promoting healthy fat management in the body. These results suggest that DCI could be a valuable ally in addressing cholesterol and obesity issues, potentially through its influence on adiponectin synthesis and its related metabolic pathways.
Read More
9
IP6 improves cholesterol levels
We examined the effects of inositol hexakisphosphate (IP6) and myo-inositol on high cholesterol in rats. In our study, we found that dietary IP6 effectively reduced increased cholesterol levels caused by a specific chemical exposure, while myo-inositol did not show significant benefits.
Additionally, IP6 also contributed to body weight gain, regardless of other dietary factors. Overall, while both inositol types helped prevent fatty liver, only IP6 demonstrated a clear advantage in managing hypercholesterolemia.
Additionally, IP6 also contributed to body weight gain, regardless of other dietary factors. Overall, while both inositol types helped prevent fatty liver, only IP6 demonstrated a clear advantage in managing hypercholesterolemia.
Read More
8
Myo-inositol reduces cholesterol levels
We wanted to understand how myo-inositol (MI), a compound found in many foods, influences cholesterol levels and overall metabolic health in db/db mice, a commonly used model for type 2 diabetes. Our findings revealed that providing MI significantly reduced high cholesterol and triglyceride levels in these mice, making a noticeable impact on their lipid profiles.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Effective relaxant
3 people found this helpful
This large package lasts four months for adults, providing good value. The small capsules are easy to swallow, and taken half an hour before breakfast, the theanine works as a relaxant without causing drowsiness, instead boosting energy and mitigating depressive symptoms. The addition of inositol helps reduce high cholesterol and supports heart health.
Read More
7.5
Stress relief benefits
1 people found this helpful
This natural antidepressant effectively eliminates stress and boosts cognitive abilities. It strengthens the immune system and improves mood without sedative effects. Theanine supports mental performance, normalises blood pressure, boosts dopamine levels, and reduces the risk of high cholesterol, diabetes, and promotes relaxation.
Read More
7.5
Calmness achieved
10 people found this helpful
It genuinely works. The quality is excellent, and after 2-3 weeks of use, I felt much calmer. I previously suffered from anxiety and panic attacks, but now, having taken it for three months, I feel significantly more relaxed. The benefits are immense, and I highly recommend it. The packaging is convenient, and the tablet size is easy to manage. I’ve noticed an increase in my overall energy throughout the day, and I'm glad to have it with me.
Read More
7.5
Cognitive function support
1 people found this helpful
This product aids relaxation while keeping me alert and promotes healthy cognitive function. The high-quality ingredients, particularly L-Theanine, help with vascular function and maintain acceptable taste. It doesn’t affect my training or muscles and assists in managing high cholesterol effectively.
Read More
7.5
Natural remedy efficacy
5 people found this helpful
This L-Theanine works remarkably well during stressful times. It's a natural alternative to anxiety and depression medications that I've relied on for years. I take it for a few weeks, then stop until I need it again. It’s proven effective and I highly recommend it.
Read More
Frequently Asked Questions
7.5
Calmness achieved
10 people found this helpful
It genuinely works. The quality is excellent, and after 2-3 weeks of use, I felt much calmer. I previously suffered from anxiety and panic attacks, but now, having taken it for three months, I feel significantly more relaxed. The benefits are immense, and I highly recommend it. The packaging is convenient, and the tablet size is easy to manage. I’ve noticed an increase in my overall energy throughout the day, and I'm glad to have it with me.
9
Effective relaxant
3 people found this helpful
This large package lasts four months for adults, providing good value. The small capsules are easy to swallow, and taken half an hour before breakfast, the theanine works as a relaxant without causing drowsiness, instead boosting energy and mitigating depressive symptoms. The addition of inositol helps reduce high cholesterol and supports heart health.
7.5
Stress relief benefits
1 people found this helpful
This natural antidepressant effectively eliminates stress and boosts cognitive abilities. It strengthens the immune system and improves mood without sedative effects. Theanine supports mental performance, normalises blood pressure, boosts dopamine levels, and reduces the risk of high cholesterol, diabetes, and promotes relaxation.
7.5
Cognitive function support
1 people found this helpful
This product aids relaxation while keeping me alert and promotes healthy cognitive function. The high-quality ingredients, particularly L-Theanine, help with vascular function and maintain acceptable taste. It doesn’t affect my training or muscles and assists in managing high cholesterol effectively.
7.5
Natural remedy efficacy
5 people found this helpful
This L-Theanine works remarkably well during stressful times. It's a natural alternative to anxiety and depression medications that I've relied on for years. I take it for a few weeks, then stop until I need it again. It’s proven effective and I highly recommend it.
8
Myo-inositol reduces cholesterol levels
We wanted to understand how myo-inositol (MI), a compound found in many foods, influences cholesterol levels and overall metabolic health in db/db mice, a commonly used model for type 2 diabetes. Our findings revealed that providing MI significantly reduced high cholesterol and triglyceride levels in these mice, making a noticeable impact on their lipid profiles.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.
Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
9
We tested the effectiveness of a food supplement combining glucomannan, D-chiro-inositol, blume, and inulin in managing high cholesterol levels among individuals with metabolic syndrome. Fifty-eight participants, each dealing with either type 2 diabetes or impaired glucose tolerance, took this supplement daily for four months alongside their metformin medication.
Over the course of the study, we observed significant improvements in several key health markers. The participants experienced a marked reduction in their body weight and body mass index (BMI). More importantly for those dealing with high cholesterol, the supplement contributed to noteworthy enhancements in their lipid profiles. Levels of total cholesterol reduced significantly, alongside improvements in triglycerides and low-density lipoprotein (LDL).
Our findings suggest that this food supplement may be a beneficial addition to traditional treatments for managing cholesterol levels and other risk factors associated with metabolic syndrome. This study highlights the potential of inositol as part of a multi-ingredient supplement, although the specific effect of inositol alone wasn't isolated.
Over the course of the study, we observed significant improvements in several key health markers. The participants experienced a marked reduction in their body weight and body mass index (BMI). More importantly for those dealing with high cholesterol, the supplement contributed to noteworthy enhancements in their lipid profiles. Levels of total cholesterol reduced significantly, alongside improvements in triglycerides and low-density lipoprotein (LDL).
Our findings suggest that this food supplement may be a beneficial addition to traditional treatments for managing cholesterol levels and other risk factors associated with metabolic syndrome. This study highlights the potential of inositol as part of a multi-ingredient supplement, although the specific effect of inositol alone wasn't isolated.
8
We enrolled 148 patients experiencing issues with high fasting glucose levels and glucose tolerance to explore the effects of a nutraceutical combination containing Berberine, Curcumin, Inositol, Banaba, and Chromium Picolinate. Over three months, participants were divided into two groups, with one taking the nutraceutical and the other a placebo. This randomized, double-blind study helped ensure the results were reliable and unbiased.
Our findings indicated that the nutraceutical combination led to improvements in metrics related to blood sugar levels and cholesterol. Specifically, we noted reductions in fasting plasma glucose, glycated hemoglobin, and total cholesterol levels. However, while inositol was one of the ingredients, the complex nature of the combination makes it difficult to isolate its individual effect on cholesterol reduction specifically.
Overall, it seems that the nutraceutical can positively impact metabolic health and may assist those with dysglycemia in improving their cholesterol levels. As we sift through the results, the potential benefits of using inositol in this blend point towards a promising avenue in managing cholesterol, though further research would be necessary to clarify its distinct role.
Our findings indicated that the nutraceutical combination led to improvements in metrics related to blood sugar levels and cholesterol. Specifically, we noted reductions in fasting plasma glucose, glycated hemoglobin, and total cholesterol levels. However, while inositol was one of the ingredients, the complex nature of the combination makes it difficult to isolate its individual effect on cholesterol reduction specifically.
Overall, it seems that the nutraceutical can positively impact metabolic health and may assist those with dysglycemia in improving their cholesterol levels. As we sift through the results, the potential benefits of using inositol in this blend point towards a promising avenue in managing cholesterol, though further research would be necessary to clarify its distinct role.
7
Inositol's cholesterol effects unclear
We explored the effects of combining metformin with two forms of inositol—myoinositol and D-chiro-inositol—on high cholesterol levels in women with polycystic ovary syndrome (PCOS). This study involved 72 participants who were randomly assigned to either metformin alone or the combination therapy for six months.
While we did observe significant improvements in other areas, such as cycle regularity and various hormonal levels, the specific impact of inositol on cholesterol was less clear. For instance, the combination therapy resulted in notable changes in average cholesterol and other metabolic parameters, but it’s important to highlight that the isolated effect of inositol on cholesterol was not explicitly measured.
Our findings suggest that while there are some benefits to this combined treatment, further research is necessary to fully understand how effective inositol alone might be on cholesterol management in women with PCOS.
While we did observe significant improvements in other areas, such as cycle regularity and various hormonal levels, the specific impact of inositol on cholesterol was less clear. For instance, the combination therapy resulted in notable changes in average cholesterol and other metabolic parameters, but it’s important to highlight that the isolated effect of inositol on cholesterol was not explicitly measured.
Our findings suggest that while there are some benefits to this combined treatment, further research is necessary to fully understand how effective inositol alone might be on cholesterol management in women with PCOS.
References
- Long L, Huang Q, Song T, Dai Z. Myo-inositol rescued insulin resistance and dyslipidemia in db/db mice. J Appl Biomed. 2024;22:74. 10.32725/jab.2024.009
- Xu Y, Gong Y, Li S, Zhou Y, Ma Z, et al. Inositol Inclusion Affects Growth, Body Composition, Antioxidant Performance, and Lipid Metabolism of Largemouth Bass (). Aquac Nutr. 2024;2024:9944159. 10.1155/2024/9944159
- Citarrella R, Chianetta R, Amodeo S, Mirarchi L, Licata A, et al. Effectiveness of a Food Supplement Based on Glucomannan, D-Chiro-Inositol, Blume and Inulin in Patients with Metabolic Syndrome. Nutrients. 2024;16. 10.3390/nu16020249
- Nani A, Bertuzzi F, Meneghini E, Mion E, Pintaudi B. Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial. J Clin Med. 2023;12. 10.3390/jcm12247650
- Tutunchi H, Arefhosseini S, Ebrahimi-Mameghani M. Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial. Clin Nutr ESPEN. 2023;54:412. 10.1016/j.clnesp.2023.02.016
- Yang Q, Zhang Y, Li L, Li J, Li Y, et al. D--Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition. Food Funct. 2022;13:7192. 10.1039/d2fo00869f
- Bahadur A, Arora H, Ravi AK, Naithani M, Bahurupi Y, et al. Comparison of Clinical, Metabolic and Hormonal Effects of Metformin Versus Combined Therapy of Metformin With Myoinositol Plus D-Chiro-Inositol in Women With Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Cureus. 2021;13:e15510. 10.7759/cureus.15510
- Derosa G, D'Angelo A, Vanelli A, Maffioli P. An Evaluation of a Nutraceutical with Berberine, Curcumin, Inositol, Banaba and Chromium Picolinate in Patients with Fasting Dysglycemia. Diabetes Metab Syndr Obes. 2020;13:653. 10.2147/DMSO.S232791
- Choi MS, Lee MK, Jung UJ, Kim HJ, Do GM, et al. Metabolic response of soy pinitol on lipid-lowering, antioxidant and hepatoprotective action in hamsters fed-high fat and high cholesterol diet. Mol Nutr Food Res. 2009;53:751. 10.1002/mnfr.200800241
- Okazaki Y, Katayama T. Dietary inositol hexakisphosphate, but not myo-inositol, clearly improves hypercholesterolemia in rats fed casein-type amino acid mixtures and 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane. Nutr Res. 2008;28:714. 10.1016/j.nutres.2008.07.003
